新着情報

2015.11.06 Achievements

2015年度 研究業績

■原著:

  1. Nagayama H,Kajimoto Y,Kumagai T,Nishiyama Y,Mishina M,Kimura K:
    Pharmacokinetics of Levodopa before and after Gastrointestinal Resection in Parkinson’s
    Disease.Case Rep Neurol 2015;7(3):181-185.
  2. Suda S,Ueda M,Nito C,Nishiyama Y,Okubo S,Abe A,Aoki J,Suzuki K,Sakamoto
    Y,Kimura K:Valproic acid ameliorates ischemic brain injury in hyperglycemic rats with
    permanent middle cerebral occlusion.Brain Res 2015;1606:1-8.
  3. Suda S,Yang B,Schaar K,Xi X,Pido J,Parsha K,Aronowski J,Savitz S:Autologous
    Bone Marrow Mononuclear Cells Exert Broad Effects on Short- and Long-Term Biological
    and Functional Outcomes in Rodents with Intracerebral Hemorrhage.Stem Cells Dev
    2015;24(23):2756-2766.
  4. Aoki J,Kimura K,Sakamoto Y:Early administration of tissue-plasminogen activator
    improves the longterm clinical outcome at 5 years after onset.J Neurol Sci 2016;362:
    33-39.
  5. Nogami A,Yamazaki M,Saito Y,Hatsuta H,Sakiyama Y,Takao M,Kimura K,Murayama
    S:Early Stage of Progressive Supranuclear Palsy:A Neuropathological Study of 324
    Consecutive Autopsy Cases.J Nippon Med Sch 2015;82(6):266-273.
  6. Kanamaru T,Kamimura N,Yokota T,Nishimaki K,Iuchi K,Lee H,Takami S,Akashiba
    H,Shitaka Y,Ueda M,Katsura K,Kimura K,Ohta S:Intravenous transplantation of
    bone marrowderived mononuclear cells prevents memory impairment in transgenic mouse
    models of Alzheimer’s disease.Brain Res 2015;1605:49-58.
  7. Sakamoto Y,Koga M,Todo K,Okuda S,Okada Y,Kimura K,Shiokawa Y,Kamiyama
    K,Furui E,Hasegawa Y,Kario K,Okata T,Kobayashi J,Tanaka E,Yamagami H,
    Nagatsuka K,Minematsu K,Toyoda K;SAMURAI study investigators:Relative systolic
    blood pressure reduction and clinical outcomes in hyperacute intracerebral hemorrhage:
    the SAMURAI-ICH observational study.J Hypertens. 2015;33(5):1069-1073.
  8. Suzuki K,Aoki J,Kanzawa T,Nishiyama Y,Takayama Y,Kimura H,Takahashi S,
    Kano T,Akaji K,Tanizaki Y,Kimura K,Mihara B:Correlation between the Occlusion
    Site and Clinical Outcome after Acute Ischemic Stroke.Intern Med 2015;54(24):
    3139-3144.
  9. Saji N,Kimura K,Yagita Y,Kawarai T,Shimizu H,Kita Y:Comparison of arteriosclerotic
    Indicators in patients with ischemic stroke:anklebrachial index, brachial-ankle pulse wave
    velocity and cardio-ankle vascular index.Hypertens Res 2015;38(5):323-328.
  10. Saji N,Kimura K,Yagita Y,Uemura J,Aoki J,Sato T,Sakurai T:Deep Cerebral
    Microbleeds and Renal Dysfunction in Patients with Acute Lacunar Infarcts.J Stroke
    Cerebrovasc Dis 2015;24(11):2572-2579.
  11. Saji N,Kimura K,Aoki J,Uemura J,Sakamoto Y:Intracranial Hemorrhage Caused by
    Non-Vitamin K Antagonist Oral Anticoagulants (NOACs)- Multicenter Retrospective
    Cohort Study in Japan.Circ J 2015;79(5):1018-1023.
  12. Hama Y,Uehara T,Ohara T,Kimura K,Okada Y,Hasegawa Y,Tanahashi N,Suzuki
    A,Takagi S,Nakagawara J,Arii K,Nagahiro S,Ogasawara K,Nagao T,Uchiyama
    S,Matsumoto M,Iihara K,Toyoda K,Minematsu K:Clinical Characteristics of Transient
    Ischemic Attack Patients with Atrial Fibrillation:Analyses of a Multicenter Retrospective
    Study.Cerebrovasc Dis Extra 2015:5(2):84-90.
  13. Toyoda K,Arihiro S,Todo K,Yamagami H,Kimura K,Furui E,Terasaki T,Shiokawa
    Y,Kamiyama K,Takizawa S,Okuda S,Okada Y,Kameda T,Nagakane Y,Hasegawa
    Y,Mochizuki H,Ito Y,Nakashima T,Takamatsu K,Nishiyama K,Kario K,Sato S,
    Koga M,SAMURAI Study Investigators:Trends in oral anticoagulant choice for acute
    stroke patients with nonvalvular atrial fibrillation in Japan:the SAMURAI-NVAF study.
    Int J Stroke 2015;10(6):836-842.
  14. Arihiro S,Todo K,Koga M,Furui E,Kinoshita N,Kimura K,Yamagami H,Terasaki
    T,Yoshimura S,Shiokawa Y,Kamiyama K,Takizawa S,Okuda S,Okada Y,Nagakane
    Y,Kameda T,Hasegawa Y,Shibuya S,Ito Y,Nakashima T,Takamatsu K,Nishiyama
    K,Matsuki T,Homma K,Takasugi J,Tokunaga K,Sato S,Kario K,Kitazono T,
    Toyoda K,SAMURAI Study Investigators:Three-month risk-benefit profile of
    anticoagulation after stroke with atrial fibrillation:The SAMURAI-Nonvalvular
    Atrial Fibrillation (NVAF) study.Int J Stroke 2016;11(5):565-574
  15. Osaki M,Koga M,Maeda K,Hasegawa Y,Nakagawara J,Furui E,Todo K,Kimura
    K,Shiokawa Y,Okada Y,Okuda S,Kario K,Yamagami H,Minematsu K,Kitazono
    T,Toyoda K:Stroke Acute Management with Urgent Risk-factor Assessment and
    Improvement (SAMURAI) Study Investigators.A multicenter, prospective, observational
    study of warfarin-associated intracerebral hemorrhage: The SAMURAI-WAICH study.J
    Neurol Sci 2015;359(1-2):72-77.
  16. Sakuta K,Saji N,Aoki J,Sakamoto Y,Shibazaki K,Iguchi Y,Kimura K:Decrease of
    Hyperintense Vessels on Fluid-Attenuated Inversion Recovery Predicts Good Outcome in
    t-PA Patients.Cerebrovasc Dis  2016;41(3-4):211-218.
  17. Oyanagi K,Yamazaki M,Hashimoyto T,Asakawa M,Wakabayashi K,Takahashi H:
    Hippocampal sclerosis in the parkinsonism-dementia complex of Guam:quantitativ
    e examination of neurons,neurofibrillary tangles, and TDP-43immunoreactivity in CA1.
    Neuropathology 2015;35(3):224-235.
  18. Oyanagi K,Mochizuki Y,Nakayama Y,Hayashi K,Shimizu T,Nagao M,Hashimoto
    T,Yamazaki M,Matsubara S,Komori T:Marked preservation of the visual and olfactory
    pathways in ALS patients in a totally locked-in state.Clinical Neuropathology 2015;
    34(5):267-274.
  19. Takumi I,Mishina M,Kominami S,Mizunari T,Kobayashi S,Teramoto A,Morita
    A:Ambient Temperature Change Increases in Stroke Onset:Analyses Based on the
    Japanese Regional Metrological Measurements.J Nippon Med Sch 2015;82(6):281-
    286.
  20. Watanabe Y,Suda S,Kanamaru T,Katsumata T,Okubo S,Kaneko T,Mii A,Sakai
    Y,Katayama Y,Kimura K,Tsuruoka S:High urinary albumin/creatinine ratio at
    admission predicts poor functional outcome in patients with acute ischemic stroke.
    Nephrology 2016.

■症例報告:

  1. Ishiwata A,Nito C,Kimura K:Lewy Body Dementia as an Underlying Etiology for
    Posterior Cortical Atrophy Initially Presented with Visual Agnosia and Alexia:A Case
    Report.J Neurol Neurophysiol 2015;6(2).
  2. Aoki J,Shibazaki K,Ito M,Saji N,Uemura J,Houkin K,Kimura K.:Unilateral moyamoya
    phenomenon with a string-of-beads appearance in an elderly patient with the c.14576G>A
    heterozygous variant of RNF213.Intern Med 2015;54(8):971-974.
  3. Muraga K,Suda S,Nagayama H,Okubo S,Abe A,Aoki J,Nogami A,Suzuki K,
    Sakamoto Y,Ueda M,Mishina M,Kimura K:Limb-shaking TIA:Cortical myoclonus
    associated with ICA stenosis.Neurology 2016;86(3):307-309.
  4. Sakamoto Y,Ouchi T,Okubo S,Abe A,Aoki J,Nogami A,Sato T,Hokama H,Ogawa
    Y,Suzuki S,Mishina M,Kimura K:Thrombolysis, Complete Recanalization, Diffusion
    Reversal, and Luxury Perfusion in Hyperacute Stroke.J Stroke Cerebrovasc Dis 2016;
    25(1):238-239.
  5. Sakamoto Y,Okubo S,Kanamaru T,Suzuki K,Kimura K:A case report of bilateral
    paramedian thalamic and occult midbrain infarctions without disturbance of consciousness.
    Neurol Sci 2015;36(8):1511-1513
  6. Saji N,Kawarai T,Miyamoto R,Sato T,Morino H,Orlacchio A,Oki R,Kimura K,
    Kaji R:Exome sequencing identifies a novel intronic mutation in ENG that causes
    recurrence of pulmonary arteriovenous malformations.J Neurol Sci 2015; 352(1-2):
    29-33.

■総説:

  1. Nagayama H,Kimura K:Depression Preceding Parkinson’s Disease Onset.Austin Alzheimers Parkinsons Dis 2015;2(2):1023-1028.