新着情報
2015.11.06 Achievements
2015年度 研究業績
■原著:
- Nagayama H,Kajimoto Y,Kumagai T,Nishiyama Y,Mishina M,Kimura K:
Pharmacokinetics of Levodopa before and after Gastrointestinal Resection in Parkinson’s
Disease.Case Rep Neurol 2015;7(3):181-185. - Suda S,Ueda M,Nito C,Nishiyama Y,Okubo S,Abe A,Aoki J,Suzuki K,Sakamoto
Y,Kimura K:Valproic acid ameliorates ischemic brain injury in hyperglycemic rats with
permanent middle cerebral occlusion.Brain Res 2015;1606:1-8. - Suda S,Yang B,Schaar K,Xi X,Pido J,Parsha K,Aronowski J,Savitz S:Autologous
Bone Marrow Mononuclear Cells Exert Broad Effects on Short- and Long-Term Biological
and Functional Outcomes in Rodents with Intracerebral Hemorrhage.Stem Cells Dev
2015;24(23):2756-2766. - Aoki J,Kimura K,Sakamoto Y:Early administration of tissue-plasminogen activator
improves the longterm clinical outcome at 5 years after onset.J Neurol Sci 2016;362:
33-39. - Nogami A,Yamazaki M,Saito Y,Hatsuta H,Sakiyama Y,Takao M,Kimura K,Murayama
S:Early Stage of Progressive Supranuclear Palsy:A Neuropathological Study of 324
Consecutive Autopsy Cases.J Nippon Med Sch 2015;82(6):266-273. - Kanamaru T,Kamimura N,Yokota T,Nishimaki K,Iuchi K,Lee H,Takami S,Akashiba
H,Shitaka Y,Ueda M,Katsura K,Kimura K,Ohta S:Intravenous transplantation of
bone marrowderived mononuclear cells prevents memory impairment in transgenic mouse
models of Alzheimer’s disease.Brain Res 2015;1605:49-58. - Sakamoto Y,Koga M,Todo K,Okuda S,Okada Y,Kimura K,Shiokawa Y,Kamiyama
K,Furui E,Hasegawa Y,Kario K,Okata T,Kobayashi J,Tanaka E,Yamagami H,
Nagatsuka K,Minematsu K,Toyoda K;SAMURAI study investigators:Relative systolic
blood pressure reduction and clinical outcomes in hyperacute intracerebral hemorrhage:
the SAMURAI-ICH observational study.J Hypertens. 2015;33(5):1069-1073. - Suzuki K,Aoki J,Kanzawa T,Nishiyama Y,Takayama Y,Kimura H,Takahashi S,
Kano T,Akaji K,Tanizaki Y,Kimura K,Mihara B:Correlation between the Occlusion
Site and Clinical Outcome after Acute Ischemic Stroke.Intern Med 2015;54(24):
3139-3144. - Saji N,Kimura K,Yagita Y,Kawarai T,Shimizu H,Kita Y:Comparison of arteriosclerotic
Indicators in patients with ischemic stroke:anklebrachial index, brachial-ankle pulse wave
velocity and cardio-ankle vascular index.Hypertens Res 2015;38(5):323-328. - Saji N,Kimura K,Yagita Y,Uemura J,Aoki J,Sato T,Sakurai T:Deep Cerebral
Microbleeds and Renal Dysfunction in Patients with Acute Lacunar Infarcts.J Stroke
Cerebrovasc Dis 2015;24(11):2572-2579. - Saji N,Kimura K,Aoki J,Uemura J,Sakamoto Y:Intracranial Hemorrhage Caused by
Non-Vitamin K Antagonist Oral Anticoagulants (NOACs)- Multicenter Retrospective
Cohort Study in Japan.Circ J 2015;79(5):1018-1023. - Hama Y,Uehara T,Ohara T,Kimura K,Okada Y,Hasegawa Y,Tanahashi N,Suzuki
A,Takagi S,Nakagawara J,Arii K,Nagahiro S,Ogasawara K,Nagao T,Uchiyama
S,Matsumoto M,Iihara K,Toyoda K,Minematsu K:Clinical Characteristics of Transient
Ischemic Attack Patients with Atrial Fibrillation:Analyses of a Multicenter Retrospective
Study.Cerebrovasc Dis Extra 2015:5(2):84-90. - Toyoda K,Arihiro S,Todo K,Yamagami H,Kimura K,Furui E,Terasaki T,Shiokawa
Y,Kamiyama K,Takizawa S,Okuda S,Okada Y,Kameda T,Nagakane Y,Hasegawa
Y,Mochizuki H,Ito Y,Nakashima T,Takamatsu K,Nishiyama K,Kario K,Sato S,
Koga M,SAMURAI Study Investigators:Trends in oral anticoagulant choice for acute
stroke patients with nonvalvular atrial fibrillation in Japan:the SAMURAI-NVAF study.
Int J Stroke 2015;10(6):836-842. - Arihiro S,Todo K,Koga M,Furui E,Kinoshita N,Kimura K,Yamagami H,Terasaki
T,Yoshimura S,Shiokawa Y,Kamiyama K,Takizawa S,Okuda S,Okada Y,Nagakane
Y,Kameda T,Hasegawa Y,Shibuya S,Ito Y,Nakashima T,Takamatsu K,Nishiyama
K,Matsuki T,Homma K,Takasugi J,Tokunaga K,Sato S,Kario K,Kitazono T,
Toyoda K,SAMURAI Study Investigators:Three-month risk-benefit profile of
anticoagulation after stroke with atrial fibrillation:The SAMURAI-Nonvalvular
Atrial Fibrillation (NVAF) study.Int J Stroke 2016;11(5):565-574 - Osaki M,Koga M,Maeda K,Hasegawa Y,Nakagawara J,Furui E,Todo K,Kimura
K,Shiokawa Y,Okada Y,Okuda S,Kario K,Yamagami H,Minematsu K,Kitazono
T,Toyoda K:Stroke Acute Management with Urgent Risk-factor Assessment and
Improvement (SAMURAI) Study Investigators.A multicenter, prospective, observational
study of warfarin-associated intracerebral hemorrhage: The SAMURAI-WAICH study.J
Neurol Sci 2015;359(1-2):72-77. - Sakuta K,Saji N,Aoki J,Sakamoto Y,Shibazaki K,Iguchi Y,Kimura K:Decrease of
Hyperintense Vessels on Fluid-Attenuated Inversion Recovery Predicts Good Outcome in
t-PA Patients.Cerebrovasc Dis 2016;41(3-4):211-218. - Oyanagi K,Yamazaki M,Hashimoyto T,Asakawa M,Wakabayashi K,Takahashi H:
Hippocampal sclerosis in the parkinsonism-dementia complex of Guam:quantitativ
e examination of neurons,neurofibrillary tangles, and TDP-43immunoreactivity in CA1.
Neuropathology 2015;35(3):224-235. - Oyanagi K,Mochizuki Y,Nakayama Y,Hayashi K,Shimizu T,Nagao M,Hashimoto
T,Yamazaki M,Matsubara S,Komori T:Marked preservation of the visual and olfactory
pathways in ALS patients in a totally locked-in state.Clinical Neuropathology 2015;
34(5):267-274. - Takumi I,Mishina M,Kominami S,Mizunari T,Kobayashi S,Teramoto A,Morita
A:Ambient Temperature Change Increases in Stroke Onset:Analyses Based on the
Japanese Regional Metrological Measurements.J Nippon Med Sch 2015;82(6):281-
286. - Watanabe Y,Suda S,Kanamaru T,Katsumata T,Okubo S,Kaneko T,Mii A,Sakai
Y,Katayama Y,Kimura K,Tsuruoka S:High urinary albumin/creatinine ratio at
admission predicts poor functional outcome in patients with acute ischemic stroke.
Nephrology 2016.
■症例報告:
- Ishiwata A,Nito C,Kimura K:Lewy Body Dementia as an Underlying Etiology for
Posterior Cortical Atrophy Initially Presented with Visual Agnosia and Alexia:A Case
Report.J Neurol Neurophysiol 2015;6(2). - Aoki J,Shibazaki K,Ito M,Saji N,Uemura J,Houkin K,Kimura K.:Unilateral moyamoya
phenomenon with a string-of-beads appearance in an elderly patient with the c.14576G>A
heterozygous variant of RNF213.Intern Med 2015;54(8):971-974. - Muraga K,Suda S,Nagayama H,Okubo S,Abe A,Aoki J,Nogami A,Suzuki K,
Sakamoto Y,Ueda M,Mishina M,Kimura K:Limb-shaking TIA:Cortical myoclonus
associated with ICA stenosis.Neurology 2016;86(3):307-309. - Sakamoto Y,Ouchi T,Okubo S,Abe A,Aoki J,Nogami A,Sato T,Hokama H,Ogawa
Y,Suzuki S,Mishina M,Kimura K:Thrombolysis, Complete Recanalization, Diffusion
Reversal, and Luxury Perfusion in Hyperacute Stroke.J Stroke Cerebrovasc Dis 2016;
25(1):238-239. - Sakamoto Y,Okubo S,Kanamaru T,Suzuki K,Kimura K:A case report of bilateral
paramedian thalamic and occult midbrain infarctions without disturbance of consciousness.
Neurol Sci 2015;36(8):1511-1513 - Saji N,Kawarai T,Miyamoto R,Sato T,Morino H,Orlacchio A,Oki R,Kimura K,
Kaji R:Exome sequencing identifies a novel intronic mutation in ENG that causes
recurrence of pulmonary arteriovenous malformations.J Neurol Sci 2015; 352(1-2):
29-33.
■総説:
- Nagayama H,Kimura K:Depression Preceding Parkinson’s Disease Onset.Austin Alzheimers Parkinsons Dis 2015;2(2):1023-1028.