新着情報

2018.11.14 Achievements

2018年度　研究業績

■原著

  1. Aoki J, Kimura K, Morita N, Harada M, Nagahiro S; YAMATO study investigators. Diabetes mellitus inhibits complete recanalization in patients with middle cerebral artery occlusion. Neurol Res. 2019 Jan;41（1）:60-67.
  2. Huber VJ, Igarashi H, Ueki S, Terumitsu-Tsujita M, Nito C, Ohno K, Suzuki Y, Itoh K, Kwee IL, Nakada T. Visualizing the Distribution of Matrix Metalloproteinases in Ischemic Brain Using In Vivo 19F-Magnetic Resonance Spectroscopic Imaging. Contrast Media Mol Imaging. 2019;2019:8908943. doi:10.1155/2019/8908943. eCollection 2019.
  3. Sakamoto Y, Okubo S, Nito C, Nishiyama Y, Suda S, Matsumoto N, Aoki J, Shimoyama T, Kanamaru T, Muraga K, Suzuki K, Mishina M, Kimura K: Ischemic stroke during anticoagulant interruption by healthcare professionals in stroke patients with atrial fibrillation. Journal of the Neurological Sciences 2019;400:113-118.
  4. Sakamoto Y, Nito C, Nishiyama Y, Suda S, Matsumoto N, Aoki J, Shimoyama T, Kanamaru T, Suzuki K, Nishimura T, Mishina M, Kimura K: Safety of Anticoagulant Therapy Including Direct Oral Anticoagulants in Patients With Acute Spontaneous Intracerebral Hemorrhage. Circulation journal 2019;83:441-446.
  5. Sakamoto Y, Nito C, Nishiyama Y, Suda S, Matsumoto N, Aoki J, Shimoyama T, Kanamaru T, Suzuki K, Go Y, Mishina M, Kimura K: Accurate etiology diagnosis in patients with stroke and atrial fibrillation: A role for brain natriuretic peptide. Journal of the Neurological Sciences 2019;400:153-157.
  6. Suda S, Aoki J, Shimoyama T, Kanamaru T, Muraga K, Suzuki K, Sakamoto Y, Kutsuna A, Nishimura T, Matsumoto N, Nito C, Nishiyama Y, Mishina M, Kimura K. Characteristics of Acute Spontaneous Intracerebral Hemorrhage in Patients Receiving Oral Anticoagulants. J Stroke Cerebrovasc Dis. 2019（1）;28:1007-14.
  7. Yokobori S, Sasaki K, Kanaya T, Igarashi Y, Nakae R, Onda H, Masuno T, Suda S, Sowa K, Nakajima M, Spurlock MS, Onn Chieng L, Hazel TG, Johe K, Gajavelli S, Fuse A, Bullock MR, Yokota H. Feasibility of Human Neural Stem Cell Transplantation for the Treatment of Acute Subdural Hematoma in a Rat Model: A Pilot Study. Front Neurol. 2019;10（2）:82.
  8. Usui G, Takayama Y, Hashimoto H, Katano T, Yanagiya M, Kusakabe M, Miura T, Matsumoto J, Horiuchi H, Okubo S. Cerebral Embolism Caused by Thrombus in the Pulmonary Vein Stump after Left Lower Lobectomy: A Case Report and Literature Review. Intern Med Advance Publication. 2019, 58（ 9） 1349-1354.
  9. Eriguchi M, Iida K, Ikeda S, Osoegawa M, Nishioka K, Hattori N, Nagayama H, Hara H. :Parkinsonism Relating to Intoxication with Glyphosate. Intern Med 2019; 58（13）:1935-1938.
  10. Nagayama H, Kano O, Murakami H, Ono K, Hamada M, Toda T, Sengoku R, Shimo Y, Hattori N.: Effect of istradefylline on mood disorders in Parkinson’s disease. J Neurol Sci 2019;396:78-83.
  11. Taguchi I, Iimuro S, Iwata H, Takashima H, Abe M, Amiya E, Ogawa T, Ozaki Y, Sakuma I, Nakagawa Y, Hibi K, Hiro T, Fukumoto Y, Hokimoto S, Miyauchi K, Yamazaki T, Ito H, Otsuji Y, Kimura K, Takahashi J, Hirayama A, Yokoi H, Kitagawa K, Urabe T, Okada Y, Terayama Y, Toyoda K, Nagao T, Matsumoto M, Ohashi Y, Kaneko T, Fujita R, Ohtsu H,Ogawa H, Daida H, Shimokawa H, Saito Y, Kimura T, Inoue T, Matsuzaki M, Nagai R.:
    High-Dose Versus Low-Dose Pitavastatin in Japanese Patients With Stable CoronaryArtery Disease （REAL-CAD）: A Randomized Superiority Trial.Circulation. 2018 May 8;137（19）:1997-2009. doi: 10.1161/CIRCULATIONAHA.117.032615. Erratum in: Circulation. 2019 Apr 2;139（14）:e836.PMID: 29735587.
  12. Usui G, Matsumoto J, Hashimoto H, Katano T, Kusakabe M, Horiuchi H, Okubo S. Thrombus Reformation in the Pulmonary Vein Stump Confirmed 16 Months After Cerebral Embolism on the Day After Left Upper Lobectomy for Lung Cancer. J Stroke Cerebrovasc Dis. 2018 Oct;27（10）:e225-e227.
  13. Sakamoto Y, Okubo S, Sekine T, Nito C, Suda S, Matsumoto N, Nishiyama Y, Aoki J, Shimoyama T, Kanamaru T, Suzuki K, Mishina M, Kimura K: Prior Direct Oral Anticoagulant Therapy is Related to Small Infarct Volume and No Major Artery Occlusion in Patients With Stroke and Non-Valvular Atrial Fibrillation. Journal of the American Heart Association 2018;7:e009507.
  14. Sakamoto Y, Okubo S, Nito C, Suda S, Matsumoto N, Nishiyama Y, Aoki J, Shimoyama T, Kanamaru T, Suzuki K, Mishina M, Kimura K: Insufficient warfarin therapy is associated with more severe stroke symptoms than no anticoagulation in patients with atrial fibrillation and acute anterior-circulation stroke.Circulation J 2018: 82（5）, 1437-1442.
  15. Aoki J, Suzuki K, Suda S, Okubo S, Mishina M, Nishiyama Y, Sakamoto Y, Kimura K: In Hyperacute Recanalization Therapy, Early Hospital Arrival Improves Outcome in Patients with Large Artery Occlusion. Eur Neurol 2018: 79（5-6）, 335-341.
  16. Hayashi T, Aoki J, Suzuki K, Sakamoto Y, Suda S, Okubo S, Mishina M, Kimura K: MRI scout images can detect the acute intracerebral hemorrhage on CT. J Neurol Sci 2018: 387, 147-149.
  17. Suda S, Shimoyama T, Nagai K, Arakawa M, Aoki J, Kanamaru T, Suzuki K, Sakamoto Y, Takeshi Y, Matsumoto N, Nishiyama Y, Nito C, Mishina M, Kimura K: Low Free Triiodothyronine Predicts 3-Month Poor Outcome After Acute Stroke. J Stroke Cerebrovasc Dis 2018: 27（10）, 2804-280.
  18. Suda S, Sakamoto Y, Okubo S, Aoki J, Shimoyama T, Kanamaru T, Suzuki K, Kutsuna A, Matsumoto N, Nito C, Nishiyama Y, Mishina M, Kimura K: Anticoagulants, Reperfusion Therapy, and Outcomes in Ischemic Stroke Patients With Non-Valvular Atrial Fibrillation　- A Single-Center, 6-Year Experience of 546 Consecutive Patients. Circ J 2018: 82（10）, 2647-2654.
  19. Sowa K, Nito C, Nakajima M, Suda S, Nishiyama Y, Sakamoto Y, Nitahara-Kasahara Y, Nakamura-Takahashi A, Ueda M, Kimura K, Okada T: Impact of Dental Pulp Stem Cells Overexpressing Hepatocyte Growth Factor after Cerebral Ischemia/Reperfusion in Rats. Molecular Therapy-Methods & Clinical Development 2018;10:281–290.
  20. Nakajima M, Suda S, Sowa K, Sakamoto Y, Nito C, Nishiyama Y, Aoki J, Ueda M, Yokobori S, Yamada M, Yokota H, Okada T, Kimura K: AMPA receptor antagonist perampanel ameliorates post-stroke functional and cognitive impairments. Neuroscience 2018; 386: 256-264
  21. Ichiyama S, Matano Y, Hoashi T, Kanda N, Nagayama H, Saeki H.: Severe myalgia associated with brodalumab treatment in a patient with psoriasis. J Dermatol 2018;45（12）:e327-e328.
  22. Matsuda H, Murata M, Mukai Y, Sako K, Ono H, Toyama H, Inui Y, Taki Y, Shimomura H, Nagayama H, Tateno A, Ono K, Murakami H, Kono A, Hirano S, Kuwabara S, Maikusa N, Ogawa M, Imabayashi E, Sato N, Takano H, Hatazawa J, Takahashi R.: Japanese multicenter database of healthy controls for [123I]FP-CIT SPECT. Eur J Nucl Med Mol Imaging 2018;45（8）:1405-1416.
  23. Suda S, Aoki J, Shimoyama T, Suzuki K, Sakamoto Y, Katano T, Okubo S, Nito C, Nishiyama Y, Mishina M, Kimura K. Low free triiodothyronine at admission predicts poststroke infection. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2018;27:397-403.
  24. Nito C, Sowa K, Nakajima M, Sakamoto Y, Suda S, Nishiyama Y, et al. Transplantation of human dental pulp stem cells ameliorates brain damage following acute cerebral ischemia. Biomedicine & pharmacotherapy 2018;108:1005-1014.
  25. Nagao T, Toyoda K, Kitagawa K, Kitazono T, Yamagami H, Uchiyama S, Tanahashi N,Matsumoto M, Minematsu K, Nagata I, Nishikawa M, Nanto S, Abe K, Ikeda Y, Ogawa A. :A noninferiority confirmatory trial of prasugrel versus clopidogrel in Japanese patients with non-cardioembolic stroke: rationale and study design for a randomized controlled trial – PRASTRO-I trial. Expert Opin Pharmacother. 2018 Apr;19（6）:529-535. doi:10.1080/14656566.2018.1444029. Epub 2018 Mar 26. PMID: 29463150.
  26. Houkin K, Shichinohe H, Abe K, Arato T, Dezawa M, Honmou O, Horie N, Katayama Y, Kudo K, Kuroda　S, Matsuyama T, Miyai I, Nagata I, Niizuma K, Sakushima K, Sasaki M, Sato N, Sawanobori K, Suda S,Taguchi A, Tominaga T, Yamamoto H, Yamashita T, Yoshimine T. Accelerating Cell Therapy for Stroke in Japan: Regulatory Framework and Guidelines on Development of Cell-Based Products. Stroke. 2018;49 （4）:e145-e52.
  27. Suzuki K, Nakajima N, Kunimoto K, Hatake S, Sakamoto Y, Hokama H, Nomura K, Hayashi T, Aoki J, Suda S, Nishiyama Y, Kimura K. Emergent Large Vessel Occlusion Screen Is an Ideal Prehospital Scale to Avoid Missing Endovascular Therapy in Acute Stroke. Stroke 2018; 49: 2096-2101.
  28. Suzuki K, Kimura K, Takeuchi M, Morimoto M, Kanazawa R, Kamiya Y, Shigeta K, Ishii N, Takayama Y, Koguchi Y, Takigawa T, Hayakawa M, Ota T, Okubo S, Naito H, Akaji K, Kato N, Inoue M, Hirano T, Miki K, Ueda T, Iguchi Y, Fujimoto S, Otsuka T, Matsumaru Y. The randomized study of endovascular therapy with versus without intravenous tissue plasminogen activator in acute stroke with ICA and M1 occlusion （SKIP study）. International journal of stroke 2019.
  29. Ogawa A, Toyoda K, Kitagawa K, Kitazono T, Nagao T, Yamagami H, Uchiyama S, Tanahashi N, Matsumoto M, Minematsu K, Nagata I, Nishikawa M, Nanto S, Abe K, IkedaY; PRASTRO-I Study Group. Comparison of prasugrel and clopidogrel in patients with non-cardioembolic ischaemic stroke: a phase 3, randomised, non-inferiority trial （PRASTRO-I）. Lancet Neurol. 2019 Mar;18（3）:238-247. doi: 10.1016/S1474-4422（18）30449-6. Epub 2019 Feb 12. PMID :30784555
  30. Yasaka M, Minematsu K, Toyoda K, Mori E, Hirano T, Hamasaki T, YamagamiH, Nagao T, Yoshimura S, Uchiyama S; RELAXED study group. Rivaroxaban administration after acute ischemic stroke: The RELAXED study. PLoS One. 2019 Feb 13;14（2）:e0212354. doi: 10.1371/journal.pone.0212354. eCollection 2019. PMID: 30759158.

■症例報告

  1. Arakawa M, Yamazaki M, Toda Y, Saito R, Ozawa A, Kosaiohira S, Kimura K:Atezolizumab-induced encephalitis in metastatic lung cancer: a case report and literature review. eNeurologicalSci. 2019 Mar; 14:49–50.
  2. Sakamoto Y, Hiruta R, Iijima A, Sakuma Y, Konno Y: Sequential Symptomatic Arterial Dissections in Multiple Vascular Beds in a Patient with Fibromuscular Dysplasia. Internal Medicine 2018;57:2885-2887.
  3. Sakamoto Y: Focal cortical superficial siderosis due to hemorrhagic transformation of cortical microinfarction. Neurological Sciences 2018;39:1635-1636.